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2021 Ford F-350 Super Duty — Used Buying Guide

5 years old · used value range $26,419 – $39,967 · max towing 35,750 lb · max payload 7,850 lb

$26,419–$39,967Used value range
4On TruckLot
35,750 lbMax towing
7,850 lbMax payload

The 2021 F-350 Super Duty at a glance

The 2021 Ford F-350 Super Duty is a 5-year-old used pickup that originally listed at approximately $72,000 for a base configuration. After 5 years of ownership-cycle depreciation, fair market value for typical-mileage examples lands between $26,419 and $39,967, with low-mileage clean-title trucks pushing toward the upper bound and higher-mileage or salvage-history trucks anchoring the lower bound.

The F-350 Super Duty at this model year was built on the Ford light-duty platform and offered in regular, extended, and crew cab body styles. Maximum trailer towing capability for this year is 35,750 lb when properly equipped (typically requires the optional max tow package and the right axle ratio); maximum payload is 7,850 lb in the lightest cab/bed/drivetrain combination.

Available engines for 2021

Powertrain7.3L Godzilla V8 Gas
Powertrain6.7L Power Stroke Diesel V8 (475 hp / 1,050 lb-ft)

Configuration options

Cab optionsCrew Cab · Extended Cab · Regular Cab
Bed options5'7" Short · 6'5" Standard · 8'0" Long
Available trimsXL, XLT, Lariat, King Ranch, Platinum, Limited
Max towing capacity35,750 lb (properly equipped)
Max payload capacity7,850 lb

EPA fuel economy ranges for this model year

Powertrain classCity mpgHighway mpg
Gasoline V61724
Gasoline V81418
Diesel2531

Common issues for the 2021 F-350 Super Duty

  • Same CP4 diesel fuel pump risk as F-250
  • DRW models have higher rear tire wear; check spare and matched tread depth
  • Gooseneck hitch hardware loosens with heavy use; verify torque on inspection
  • Heavy-duty trucks live hard lives — verify service intervals were met

Service history matters more on this model year than mileage alone. A 2021 F-350 Super Duty with documented oil changes, transmission services performed at the recommended interval, and any open recalls completed is worth meaningfully more than an undocumented truck of the same mileage. Ask the seller for the maintenance binder; if it does not exist, ask the local Ford dealership to pull the VIN history before you commit to a price.

2021 F-350 Super Duty listings on TruckLot

Trim & BodyMilesPriceState
Limited
Extended Cab
60,616 mi $31,161 Juneau, Alaska
King Ranch
Extended Cab
72,032 mi $30,822 Baltimore, Maryland
Lariat
Extended Cab
75,975 mi $32,855 Peoria, Illinois
Lariat
Crew Cab
64,743 mi $35,903 Harrisburg, Pennsylvania

Should you buy a 2021 F-350 Super Duty right now?

The honest answer depends on three variables: how the truck was used, what powertrain it has, and what comparable competitors are listed for in your state. A 2021 F-350 Super Duty with a clean service history, the volume powertrain (avoid first-year-of-production engines unless you have done your homework), and a price near the middle of the $26,419–$39,967 range is usually a sound buy.

If you are cross-shopping the same model year against competitors, our comparison guides work through the trade-offs with real numbers. Diesel premium, towing differences, payload differences, and depreciation curves are all spelled out so you can decide whether the $3,000–$8,000 difference between similar trucks is justified for your use case.